Round Two of playing with EMaD has gone much better for me, so now I can comment on a functional install (which is so much better than a non-functional one!).
With Bizzen, I didn't realize he was supposed to shock me constantly until I found his home. It's simultaneously amusing and annoying. I'm really glad this part of the mod wasn't working any better than the cutscene trigger in my first game, since I carted that bee around with me for a couple of weeks.
I absolutely adore the wolf. Having a pet following my ranger around is great. I do have a few little observations though. On reaching Brynnlaw, Betana shapeshifts and reveals herself, but her speech indicates we never had a final confrontation with Moxen (and that we didn't know she wasn't really a wolf), which we did.
Another odd behavior results from the way Betana spawns to Charname: she's present in dreams. This was only problematic in trying to keep her away from Bhaal in the Asylum dream, as I couldn't very well tell her to stay there. There's also a typo in her interaction menu: "Pull the her tail." I assume that's from not fully changing it from "Pull the wolf's tail."
At any rate, everything seems to work great now. I don't know why the first install was so broken. There are a number of smaller mods I removed completely for Round Two, and QP and UB are now installed before EMaD instead of after, but I'm not sure any of these changes are even relevant.